Facile synthesis of bis(indolyl)methanes using catalytic amount of iodine at room temperature under solvent-free conditions

被引：298

作者：

Ji, SJ ^{[1
]}

Wang, SY

Zhang, Y

Loh, TP

机构：

[1] Suzhou Univ, Coll Chem & Chem Engn, Suzhou 215006, Peoples R China

[2] Suzhou Univ, Key Lab Organ Synth Jiangsu Prov, Suzhou 215006, Peoples R China

[3] Natl Univ Singapore, Dept Chem, Singapore 117543, Singapore

来源：

TETRAHEDRON | 2004年 / 60卷 / 09期

基金：

中国国家自然科学基金;

关键词：

solvent-free; iodine; indoles; aldehydes; bis(indolyl)methanes;

D O I：

10.1016/j.tet.2003.12.060

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Efficient electrophilic substitution reactions of indoles with various aromatic aldehydes were carried out using a catalytic amount of I-2 under solvent-free conditions to afford the corresponding bis(indolyl)methanes in excellent yields. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：2051 / 2055

页数：5

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