mRNA quality control: Marking the message for life or death

被引：80

作者：

Lykke-Andersen, J ^{[1
]}

机构：

[1] Yale Univ, Sch Med, Dept Mol Biophys & Biochem, New Haven, CT 06536 USA

来源：

CURRENT BIOLOGY | 2001年 / 11卷 / 03期

关键词：

D O I：

10.1016/S0960-9822(01)00036-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A protein complex deposited upstream of exon-exon junctions after pre-mRNA splicing may serve a dual role in mRNA quality control by directing mRNA nuclear export and, possibly, serving as a downstream 'mark' for nonsense-mediated decay.

引用

页码：R88 / R91

页数：4

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