Progress in the noninvasive, in-vivo, tissue modulated Raman spectroscopy of human blood

被引：14

作者：

Chaiken, J ^{[1
]}

Finney, WF ^{[1
]}

Yang, XK ^{[1
]}

Knudson, PE ^{[1
]}

Peterson, KP ^{[1
]}

Peterson, CM ^{[1
]}

Weinstock, RS ^{[1
]}

Hagrman, D ^{[1
]}

机构：

[1] Syracuse Univ, Ctr Sci & Technol 1 014, Dept Chem, Syracuse, NY 13244 USA

来源：

BIOMEDICAL DIAGNOSTIC, GUIDANCE, AND SURGICAL-ASSIST SYSTEMS III | 2001年 / 4254卷

关键词：

noninvasive; in vivo Raman spectroscopy; Blood Analysis; microcirculation;

D O I：

10.1117/12.427936

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

We have recently presented the first Raman spectra of in vivo human blood. A brief review of how to obtain such spectra and normalize them to the appropriate blood volume is given showing how to produce spectra that can be used for noninvasive quantitative analysis of blood in vivo. New clinical data from individuals and groups completely reproduce and extend all the earlier results. These new data reveal how certain small differences between individuals result in some variability in their noninvasive quantitation. We show the origin of this variability and how to obtain quantitative corrections based entirely on the individual measurement and tabulated data.

引用

页码：216 / 227

页数：12

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