CELL BIOLOGY Neither brown nor white

被引：36

作者：

Cannon, Barbara ^{[1
]}

Nedergaard, Jan ^{[1
]}

机构：

[1] Stockholm Univ, Wenner Gren Inst, SE-10691 Stockholm, Sweden

来源：

NATURE | 2012年 / 488卷 / 7411期

关键词：

ADIPOSE-TISSUE; ADULT HUMANS; ADIPOCYTES; FAT; DISTINCT; EXPRESSION; STRESS; MOUSE; MICE;

D O I：

10.1038/488286a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Fat cells are usually thought of as being either energy-storing white fat cells or food-burning brown fat cells. The identification of a third type of fat cell in mice and humans might open up new avenues for combating obesity.

引用

页码：286 / 287

页数：3

共 16 条

[1] BROWN ADIPOSE TISSUE AND HEAT PRODUCTION IN NEWBORN INFANT [J].

AHERNE, W ;

HULL, D .

JOURNAL OF PATHOLOGY AND BACTERIOLOGY, 1966, 91 (01) :223-&

[2] Developmental biology - Neither fat nor flesh [J].

Cannon, Barbara ;

Nedergaard, Jan .

NATURE, 2008, 454 (7207) :947-948

[3] CL316,243 and cold stress induce heterogeneous expression of UCP1 mRNA and protein in rodent brown adipocytes [J].

Cinti, S ;

Cancello, R ;

Zingaretti, MC ;

Ceresi, E ;

De Matteis, R ;

Giordano, A ;

Himms-Hagen, J ;

Ricquier, D .

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 2002, 50 (01) :21-31

[4] Identification and Importance of Brown Adipose Tissue in Adult Humans. [J].

Cypess, Aaron M. ;

Lehman, Sanaz ;

Williams, Gethin ;

Tal, Ilan ;

Rodman, Dean ;

Goldfine, Allison B. ;

Kuo, Frank C. ;

Palmer, Edwin L. ;

Tseng, Yu-Hua ;

Doria, Alessandro ;

Kolodny, Gerald M. ;

Kahn, C. Ronald .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 360 (15) :1509-1517

[5] UCP1 Ablation Induces Obesity and Abolishes Diet-induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality [J].

Feldmann, Helena M. ;

Golozoubova, Valeria ;

Cannon, Barbara ;

Nedergaard, Jan .

CELL METABOLISM, 2009, 9 (02) :203-209

[6] Emergence of brown adipocytes in white fat in mice is under genetic control - Effects on body weight and adiposity [J].

Guerra, C ;

Koza, RA ;

Yamashita, H ;

Walsh, K ;

Kozak, LP .

JOURNAL OF CLINICAL INVESTIGATION, 1998, 102 (02) :412-420

[7]

Lichtenbelt WDV, 2009, NEW ENGL J MED, V360, P1500, DOI 10.1056/NEJMoa0808718

[8] Unexpected evidence for active brown adipose tissue in adult humans [J].

Nedergaard, Jan ;

Bengtsson, Tore ;

Cannon, Barbara .

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2007, 293 (02) :E444-E452

[9] Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes [J].

Petrovic, Natasa ;

Walden, Tomas B. ;

Shabalina, Irina G. ;

Timmons, James A. ;

Cannon, Barbara ;

Nedergaard, Jan .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 285 (10) :7153-7164

[10] High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans Effects of Cold Exposure and Adiposity [J].

Saito, Masayuki ;

Okamatsu-Ogura, Yuko ;

Matsushita, Mami ;

Watanabe, Kumiko ;

Yoneshiro, Takeshi ;

Nio-Kobayashi, Junko ;

Iwanaga, Toshihiko ;

Miyagawa, Masao ;

Kameya, Toshimitsu ;

Nakada, Kunihiro ;

Kawai, Yuko ;

Tsujisaki, Masayuki .

DIABETES, 2009, 58 (07) :1526-1531

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