A study of the microbiological reduction of alpha,beta-unsaturated carbonyl ent-Kaurenes by Gibberella fujikuroi

被引：13

作者：

Fraga, BM ^{[1
]}

Gonzalez, P ^{[1
]}

Guillermo, R ^{[1
]}

Hernandez, MG ^{[1
]}

机构：

[1] UNIV LA LAGUNA,DEPT QUIM ORGAN,TENERIFE,SPAIN

来源：

TETRAHEDRON | 1996年 / 52卷 / 43期

关键词：

D O I：

10.1016/0040-4020(96)00837-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The incubation of 18-hydroxy-15-oxo-ent-kaur-16-ene with the fungus Gibberella fujikuroi gave 16 alpha,17-dihydro-15-oxo derivatives, whilst the feeding of 3-oxo-15 alpha,16 alpha-epoxy-ent-kaur-1-ene afforded a series of products, which conserve the 1,2-double bond. These results indicated that the hydrogenation of alpha,beta-unsaturated carbonyl compounds with an ent-kaurene skeleton by this fungus is a stereospecific and regiospecific reduction, that does not depend on the biosynthetic route of gibberellins and kaurenolides. Copyright (C) 1996 Published by Elsevier Science Ltd

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页码：13767 / 13782

页数：16

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