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THE BIOTRANSFORMATION OF 2 ENT-15-BETA,16-BETA-EPOXY-KAURANE DERIVATIVES BY GIBBERELLA-FUJIKUROI

被引：13
作者：
FRAGA, BM
HERNANDEZ, MG
GARCIATELLADO, F
GONZALEZ, P
PERALES, A
机构：
[1] CSIC,INST ROCASOLANO,DEPT RAYOS X,E-28016 MADRID,SPAIN
[2] UNIV LA LAGUNA,DEPT QUIM ORGAN,LA LAGUNA,SPAIN
来源：
PHYTOCHEMISTRY | 1993年 / 34卷 / 01期
关键词：
GIBBERELLA-FUJIKUROI; MICROBIOLOGICAL TRANSFORMATIONS; DITERPENES; ENT-15-BETA; 16-BETA-EPOXY-14-ALPHA-HYDROXYKAURANE; SIDEROXOL;
D O I：
10.1016/S0031-9422(00)90794-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The microbiological transformation of the diterpene ent-15beta,16beta-epoxy-14alpha-hydroxykaurane into ent-14alpha,15beta-dihydroxy-11alpha,16alpha-epoxykaurane, ent-7alpha,14alpha,15beta-trihydroxy-11alpha,16alpha-epoxykaurane and ent-7beta,14alpha,15beta-trihydroxy-11alpha,16alpha-epoxykaurane has been carried out using the fungus Gibberella fujikuroi. The incubation with this fungus of sideroxol (ent-7alpha,18-dihydroxy-15beta,16beta-epoxykaurane) gave as main products ent-7alpha,15beta,18-trihydroxy-11alpha,16alpha-epoxykaurane and ent-7alpha,13,18-trihydroxy-15alpha,16alpha-epoxykauranc. Some of these compounds were identified as their acetate derivatives. The presence of the 15alpha,16alpha-epoxy group in these two substrates inhibits transformations involving oxidation at C-19 and favours the hydroxylation at C-11(beta).
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页码：133 / 138
页数：6
相关论文
共 23 条
[1]  
BEURSKENS PT, 1982, DIRECT METHODS DIFFE
[2]  
BRETON JL, 1969, TETRAHEDRON LETT, P599
[3]   EFFECT OF PLANT GROWTH RETARDANTS ON BIOSYNTHESIS OF DITERPENES BY GIBBERELLA FUJIKUROI [J].
CROSS, BE ;
MYERS, PL .
PHYTOCHEMISTRY, 1969, 8 (01) :79-&
[4]   AN ENZYMIC SITE OF INHIBITION OF GIBBERELLIN BIOSYNTHESIS BY AMO 1618 AND OTHER PLANT GROWTH RETARDANTS [J].
DENNIS, DT ;
UPPER, CD ;
WEST, CA .
PLANT PHYSIOLOGY, 1965, 40 (05) :948-&
[5]   THE MICROBIOLOGICAL TRANSFORMATION OF SOME ENT-7-ALPHA,15-BETA-DIHYDROXYKAURENE DERIVATIVES BY GIBBERELLA-FUJIKUROI [J].
FRAGA, BM ;
HERNANDEZ, MG ;
GONZALEZ, P .
PHYTOCHEMISTRY, 1991, 30 (08) :2567-2571
[6]   THE MICROBIOLOGICAL TRANSFORMATION OF SOME ENT-KAUR-16-ENE 7-ALCOHOLS, 15-ALCOHOLS AND 18-ALCOHOLS BY GIBBERELLA-FUJIKUROI [J].
FRAGA, BM ;
HANSON, JR ;
HERNANDEZ, MG ;
SARAH, FY .
PHYTOCHEMISTRY, 1980, 19 (06) :1087-1091
[7]   THE MICROBIOLOGICAL TRANSFORMATION OF CANDIDIOL, ENT-15-BETA,18-DIHYDROXY-KAUR-16-ENE, BY GIBBERELLA-FUJIKUROI [J].
FRAGA, BM ;
GONZALEZ, P ;
HERNANDEZ, MG ;
TELLADO, FG ;
PERALES, A .
PHYTOCHEMISTRY, 1986, 25 (05) :1235-1237
[8]   BIOTRANSFORMATION OF 2 ENT-15-BETA-HYDROXY-KAUR-16-ENE DERIVATIVES BY GIBBERELLA-FUJIKUROI [J].
FRAGA, BM ;
HERNANDEZ, MG ;
GONZALEZ, P .
PHYTOCHEMISTRY, 1992, 31 (11) :3845-3849
[9]   THE MICROBIOLOGICAL TRANSFORMATION OF SOME ENT-15-BETA-HYDROXYKAURENES BY GIBBERELLA-FUJIKUROI [J].
FRAGA, BM ;
HERNANDEZ, MG ;
DIAZ, CE ;
GONZALEZ, P ;
GUILLERMO, R .
PHYTOCHEMISTRY, 1988, 27 (10) :3131-3136
[10]   THE INHIBITION OF GIBBERELLIC-ACID BIOSYNTHESIS BY ENT-KAURAN-16-BETA, 17-EPOXIDE [J].
HANSON, JR ;
WILLIS, CL ;
PARRY, KP .
PHYTOCHEMISTRY, 1980, 19 (11) :2323-2325
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