Syntheses of vinylindoles via a Bronsted acid catalyzed highly regio- and stereoselective cis-hydroarylation of ynamides

被引：62

作者：

Zhang, Y ^{[1
]}

机构：

[1] GE Global Res Ctr, Niskayuna, NY 12308 USA

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 38期

基金：

美国国家科学基金会;

关键词：

ynamides; vinylindole; hydroarylation;

D O I：

10.1016/j.tetlet.2005.07.098

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly regio- and stereoselective Bronsted acid-catalyzed coupling of ynamides and indoles is described. This process is the equivalent of hydroarylation of ynamides and leads to the efficient syntheses of vinylindoles. Diels-Alder reaction between the vinylindoles and DMAD afforded carbazole derivatives in good yields. (c) 2005 Elsevier Ltd. All rights reserved.

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页码：6483 / 6486

页数：4

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