Highly sensitive fluorescent probes for zinc ion based on triazolyl-containing tetradentate coordination motifs

被引：187

作者：

Huang, Sha ^{[1
]}

Clark, Ronald J. ^{[1
]}

Zhu, Lei ^{[1
]}

机构：

[1] Florida State Univ, Dept Chem & Biochem, Tallahassee, FL 32306 USA

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 24期

关键词：

D O I：

10.1021/ol702208y

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two new 1,2,3-triazolyl-containing N4-tetradentate ligands show nanomolar affinity for Zn2+ under physiological conditions. Furthermore, they are easily derivatizable to afford fluorescent probes suitable for sensitive Zn2+ detection. Structural characterizations in both solid and solution states suggest that N3 and N2 in the 1,2,3-triazolyl moiety coordinate with Zn2+ in A and B to afford five-membered and six-membered coordination rings, respectively. The probes show sensitive fluorescence enhancement and ratiometric responses to Zn2+.

引用

页码：4999 / 5002

页数：4

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