Current evidence of tissue engineering for dentine regeneration in animal models: a systematic review

被引:16
作者
da Silva, Gabriela S. [1 ]
Moreira, Maria Stella [1 ]
Fukushima, Karen A. [1 ]
Raggio, Daniela P. [2 ]
Mello-Moura, Anna Carolina V. [1 ]
Lara, Juan S. [3 ]
Gimenez, Thais [1 ]
Allegrini Junior, Sergio [1 ]
Morimoto, Susana [1 ]
Tedesco, Tamara K. [1 ]
机构
[1] Univ Ibirapuera, Grad Program Dent, BR-04661100 Sao Paulo, SP, Brazil
[2] Univ Sao Paulo, Sch Dent, Dept Orthodont & Pediat Dent, BR-05508000 Sao Paulo, SP, Brazil
[3] Indiana Univ, Sch Dent, Dept Cariol Operat Dent & Dent Publ Hlth, Indianapolis, IN 46202 USA
关键词
dental caries; dental pulp capping; dentine; stem cells; systematic review; tissue engineering; tissue scaffolds; tooth injuries; MINERAL TRIOXIDE AGGREGATE; CALCIUM HYDROXIDE; ODONTOGENIC DIFFERENTIATION; PULP; SCAFFOLDS; PROTEINS; TEETH; TOOTH;
D O I
10.2217/rme-2019-0005
中图分类号
Q813 [细胞工程];
学科分类号
100113 [医学细胞生物学];
摘要
Aim: The aim of this study is to verify the type of scaffold effect on tissue engineering for dentine regeneration in animal models. Materials & methods: Strategic searches were conducted through MEDLINE/PubMed, Web of Science and Scopus databases. The studies were included with the following eligibility criteria: studies evaluating dentine regeneration, and being an in vivo study. Results: From 1392 identified potentially relevant studies, 15 fulfilled the eligibility criteria. All studies described characteristics of neoformed dentine, being that the most reported reparative dentine formation. Most of included studies presented moderate risk of bias. Conclusion: Up to date scientific evidence shows a positive trend to dentine regeneration when considering tissue engineering in animal models, regardless the type of scaffolds used.
引用
收藏
页码:1345 / 1360
页数:16
相关论文
共 33 条
[1]
Mineral trioxide aggregate (MTA) and calcium hydroxide as pulp-capping agents in human teeth: a preliminary report [J].
Aeinehchi, M ;
Eslami, B ;
Ghanbariha, M ;
Saffar, AS .
INTERNATIONAL ENDODONTIC JOURNAL, 2003, 36 (03) :225-231
[2]
Akhlaghi Najmeh, 2015, Dent Res J (Isfahan), V12, P406
[3]
Histomorphometric and Micro-computed Tomography Analysis of Pulpal Response to Three Different Pulp Capping Materials [J].
Al-Hezaimi, Khalid ;
Salameh, Ziad ;
Al-Fouzan, Khalid ;
Al Rejaie, Mansour ;
Tay, Franklin R. .
JOURNAL OF ENDODONTICS, 2011, 37 (04) :507-512
[4]
Biomimetic Approach to Perforation Repair Using Dental Pulp Stem Cells and Dentin Matrix Protein 1 [J].
Alsanea, Rajaa ;
Ravindran, Sriram ;
Fayad, Mohamed I. ;
Johnson, Bradford R. ;
Wenckus, Christopher S. ;
Hao, Jianjun ;
George, Anne .
JOURNAL OF ENDODONTICS, 2011, 37 (08) :1092-1097
[5]
Histological assessment of regenerative endodontic treatment in animal studies with different scaffolds: A systematic review [J].
Altaii, Milad ;
Richards, Lindsay ;
Rossi-Fedele, Giampiero .
DENTAL TRAUMATOLOGY, 2017, 33 (04) :235-244
[6]
Bjorndal L, 2001, QUINTESSENCE INT, V32, P717
[7]
Nanocrystalline calcium sulfate/hydroxyapatite biphasic compound as a TGF-β1/VEGF reservoir for vital pulp therapy [J].
Chiang, Yu-Chih ;
Chang, Hao-Hueng ;
Wong, Ching-Ching ;
Wang, Yi-Ping ;
Wang, Yin-Lin ;
Huang, Wen-Hsuan ;
Lin, Chun-Pin .
DENTAL MATERIALS, 2016, 32 (10) :1197-1208
[8]
Effect of Leptin on Odontoblastic Differentiation and Angiogenesis: An In Vivo Study [J].
Choi, Sung-Hyeon ;
Jang, Ji-Hyun ;
Koh, Jeong-Tae ;
Chang, Hoon-Sang ;
Hwang, Yun-Chan ;
Hwang, In-Nam ;
Lee, Bin-Na ;
Oh, Won-Mann .
JOURNAL OF ENDODONTICS, 2019, 45 (11) :1332-1341
[9]
Long-term evaluation of direct pulp capping-treatment outcomes over an average period of 6.1 years [J].
Dammaschke, Till ;
Leidinger, Jana ;
Schaefer, Edgar .
CLINICAL ORAL INVESTIGATIONS, 2010, 14 (05) :559-567
[10]
Autologous Platelet Concentrates for Pulp and Dentin Regeneration: A Literature Review of Animal Studies [J].
Del Fabbro, Massimo ;
Lolato, Alessandra ;
Bucchi, Cristina ;
Taschieri, Silvio ;
Weinstein, Roberto L. .
JOURNAL OF ENDODONTICS, 2016, 42 (02) :250-257