Expanding screening space through the use of alternative reservoirs in vapor-diffusion experiments

被引:35
作者
Newman, J [1 ]
机构
[1] In Stilla Consulting, Encinitas, CA 92024 USA
来源
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY | 2005年 / 61卷
关键词
D O I
10.1107/S0907444905002726
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Setting up vapor-diffusion crystallization experiments against four different reservoir solutions showed that the reservoir solution may have a profound effect on the outcome of a crystallization experiment. This suggests that a facile way to increase crystallization space through screening is not to add more crystallization conditions to the process, but to set up the same conditions over different reservoirs.
引用
收藏
页码:490 / 493
页数:4
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