The advantages of using a modified microbatch method for rapid screening of protein crystallization conditions

被引：69

作者：

D'Arcy, A ^{[1
]}

Mac Sweeney, A

Stihle, M

Haber, A

机构：

[1] Morphochem AG Basel, Basel, Switzerland

[2] Univ Freiburg, D-7800 Freiburg, Germany

来源：

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY | 2003年 / 59卷

关键词：

D O I：

10.1107/S0907444902022011

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

In this study, characterization and optimization of a modified microbatch crystallization technique has been attempted in order to provide a rapid screening method. Using this method for screening has certain advantages over standard vapour-diffusion methods: no sealing of drops is required, no reservoir solutions are needed and the experiments can easily be performed over a range of temperatures.

引用

页码：396 / 399

页数：4

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