Recent advances in DNA nanotechnology

被引：109

作者：

Chidchob, Pongphak ^{[1
]}

Sleiman, Hanadi F. ^{[1
]}

机构：

[1] McGill Univ, Dept Chem, 801 Sherbrooke St West, Montreal, PQ H3A 0B8, Canada

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 2018年 / 46卷

基金：

加拿大自然科学与工程研究理事会;

关键词：

SEQUENCE-DEFINED POLYMERS; NANOSCALE SHAPES; NUCLEIC-ACIDS; LIVING CELLS; FOLDING DNA; NANOSTRUCTURES; ORIGAMI; TETRAHEDRON; TEMPERATURE; MOLECULES;

D O I：

10.1016/j.cbpa.2018.04.012

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

DNA is a powerful guiding molecule to achieve the precise construction of arbitrary structures and high-resolution organization of functional materials. The combination of sequence programmability, rigidity and highly specific molecular recognition in this molecule has resulted in a wide range of exquisitely designed DNA frameworks. To date, the impressive potential of DNA nanomaterials has been demonstrated from fundamental research to technological advancements in materials science and biomedicine. This review presents a summary of some of the most recent developments in structural DNA nanotechnology regarding new assembly approaches and efforts in translating DNA nanomaterials into practical use. Recent work on incorporating blunt-end stacking and hydrophobic interactions as orthogonal instruction rules in DNA assembly, and several emerging applications of DNA nanomaterials will also be highlighted.

引用

页码：63 / 70

页数：8

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