Overexpression of the response regulator evgA of the two-component signal transduction system modulates multidrug resistance conferred by multidrug resistance transporters

被引：96

作者：

Nishino, K

Yamaguchi, A

机构：

[1] Osaka Univ, Inst Sci & Ind Res, Dept Cell Membrane Biol, Ibaraki, Osaka 5670047, Japan

[2] Osaka Univ, Fac Pharmaceut Sci, Suita, Osaka 5650871, Japan

[3] Japan Sci & Technol Corp, CREST, Osaka 5670047, Japan

来源：

JOURNAL OF BACTERIOLOGY | 2001年 / 183卷 / 04期

关键词：

D O I：

10.1128/JB.183.4.1455-1458.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Overexpression of evgA, a response regulator of a two-component system, increased multidrug efflux in Escherichia coli, Since overexpression of the emrKY operon, which is controlled by evgAS, could account only for deoxycholate resistance, the evgAS locus apparently controls expression of at least one other multidrug efflux operon.

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页码：1455 / 1458

页数：4

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