Minimally invasive necrosectomy for infected necrotizing pancreatitis

被引:62
作者
Bucher, Pascal [1 ]
Pugin, Francois [1 ]
Morel, Philippe [1 ]
机构
[1] Hop Cantonal Univ Geneva, Dept Surg, Clin Visceral & Transplantat Surg, CH-1211 Geneva 14, Switzerland
关键词
laparoscopy; pancreatitis; necrosis; infection; necrotizing pancreatitis; necrosectomy;
D O I
10.1097/MPA.0b013e3181514c9e
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Objectives: Infected necrotizing pancreatitis represents a serious and therapeutically challenging complication. Percutaneous drainage of infected pancreatic necrosis is often unsuccessful. Alternatively, open necrosectomies are associated with high morbidity. Recently, minimally invasive necrosectomy techniques have been tried with satisfying results; however, they frequently necessitate multiple sessions for definitive necrosectomy. To evaluate results of single large-port laparoscopic necrosectomy for proven infected necrotizing pancreatitis. Methods: Eight patients presenting proven infected pancreatic necrosis during course of acute pancreatitis and not responding to radiological drainage were prospectively offered minimally invasive necrosectomy. Laparoscopic necrosectomy were performed using a single large port placed along the drain tract directly into the infected necrosis. In all patients, drainage was placed during laparoscopic necrosectomy for continuous postoperative lavage. Results: No perioperative complications were recorded with a median operative time of 87 T 42 minutes. No blood transfusions were needed. No surgical postoperative morbidity and mortality were recorded. In all cases, except for one patient with multiple abscesses, only one session of necrosectomy was sufficient to completely clear the necrotic abscess. Laparoscopic necrosectomy was successful in all patients, and none required complementary surgical or radiological treatment. Conclusions: Minimally invasive necrosectomy has been safe and highly efficient through single large-port laparoscopy for infected pancreatic necrosis in our series of patients. Minimally invasive necrosectomy is a promising technique for infected necrotizing pancreatitis and should be regarded as a valid therapeutic option for necrotizing pancreatitis.
引用
收藏
页码:113 / 119
页数:7
相关论文
共 33 条
[21]   Evidence-based treatment of acute pancreatitis -: A look at established paradigms [J].
Heinrich, S ;
Schäfer, M ;
Rousson, V ;
Clavien, PA .
ANNALS OF SURGERY, 2006, 243 (02) :154-168
[22]   Laparoscopic assisted percutaneous drainage of infected pancreatic necrosis [J].
Horvath, KD ;
Kao, LS ;
Ail, A ;
Wherry, KL ;
Pellegrini, CA ;
Sinanan, MN .
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2001, 15 (07) :677-682
[23]   A technique for laparoscopic-assisted percutaneous drainage of infected pancreatic necrosis and pancreatic abscess [J].
Horvath, KD ;
Kao, LS ;
Wherry, KL ;
Pellegrini, CA ;
Sinanan, MN .
SURGICAL ENDOSCOPY-ULTRASOUND AND INTERVENTIONAL TECHNIQUES, 2001, 15 (10) :1221-1225
[24]   UK guidelines for the management of acute pancreatitis [J].
Johnson, CD ;
Charnley, R ;
Rowlands, B ;
Carter, R ;
Bassi, C ;
Chalmers, A ;
Imrie, CW ;
Larvin, M ;
Mitchell, CJ ;
Neoptolemos, JM ;
Siriwardena, A ;
Aly, E ;
Butturini, G ;
Kelly, J .
GUT, 2005, 54 :1-9
[25]   Interventional and surgical treatment of pancreatic abscess [J].
Mithofer, K ;
Mueller, PR ;
Warshaw, AL .
WORLD JOURNAL OF SURGERY, 1997, 21 (02) :162-168
[26]   Laparoscopic-assisted pancreatic necrosectomy - A new surgical option for treatment of severe necrotizing pancreatitis [J].
Parekh, Dilip .
ARCHIVES OF SURGERY, 2006, 141 (09) :895-902
[27]   Surgical treatment of necrotizing pancreatitis by necrosectomy and closed lavage: Changing patient characteristics and outcome in a 19-year, single-center series [J].
Rau, B ;
Bothe, A ;
Beger, HG .
SURGERY, 2005, 138 (01) :28-39
[28]   Severe acute pancreatitis:: Case-oriented discussion of interdisciplinary management [J].
Renzulli, P ;
Jakob, SM ;
Täuber, M ;
Candinas, D ;
Gloor, B .
PANCREATOLOGY, 2005, 5 (2-3) :145-156
[29]   Percutaneous video-assisted necrosectorny for infected pancreatic necrosis [J].
Risse, O ;
Auguste, T ;
Delannoy, P ;
Cardin, N ;
Bricault, I ;
Létoublon, CL .
GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE, 2004, 28 (10) :868-871
[30]   Effect of a pneumoperitoneum on systemic cytokine levels, bacterial translocation, and organ complications in a rat model of severe acute pancreatitis with infected necrosis [J].
Strobel, O. ;
Wachter, D. ;
Werner, J. ;
Uhl, W. ;
Mueller, C. A. ;
Khalik, M. ;
Geiss, H. K. ;
Fiehn, W. ;
Buechler, M. W. ;
Gutt, C. N. .
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2006, 20 (12) :1897-1903