Design of near-infrared imaging probe with the assistance of ultrasound localization

被引:29
作者
Zhu, Q [1 ]
Chen, NG [1 ]
Piao, DQ [1 ]
Guo, PY [1 ]
Ding, XH [1 ]
机构
[1] Univ Connecticut, Dept Elect & Comp Engn, Storrs, CT 06269 USA
关键词
D O I
10.1364/AO.40.003288
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
A total of 364 optical source-detector pairs were deployed uniformly over a 9 cm x 9 cm probe area initially, and then the total pairs were reduced gradually to 60 in experimental and simulation studies. For each source-detector configuration, three-dimensional (3-D) images of a 1-cm-diameter absorber of different contrasts were reconstructed from the measurements made with a frequency-domain system. The results have shown that more than 160 source-detector pairs are needed to reconstruct the absorption coefficient to within 60% of the true value and appropriate spatial and contrast resolution. However, the error in target depth estimated from 3-D images was more than 1 cm in all source-detector configurations. With the a priori target depth information provided by ultrasound, the accuracy of the reconstructed absorption coefficient was improved by 15% and 30% on average, and the beam width was improved by 24% and 41% on average for high- and low-contrast cases, respectively. The speed of reconstruction was improved by ten times on average. (C) 2001 Optical Society of America.
引用
收藏
页码:3288 / 3303
页数:16
相关论文
共 24 条
[1]   SCATTERING OF DIFFUSE PHOTON DENSITY WAVES BY SPHERICAL INHOMOGENEITIES WITHIN TURBID MEDIA - ANALYTIC SOLUTION AND APPLICATIONS [J].
BOAS, DA ;
OLEARY, MA ;
CHANCE, B ;
YODH, AG .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (11) :4887-4891
[2]   Regional imager for low-resolution functional imaging of the brain with diffusing near-infrared light [J].
Danen, RM ;
Wang, Y ;
Li, XD ;
Thayer, WS ;
Yodh, AG .
PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1998, 67 (01) :33-40
[3]   Assessment of the size, position, and optical properties of breast tumors in vivo by noninvasive optical methods [J].
Fantini, S ;
Walker, SA ;
Franceschini, MA ;
Kaschke, M ;
Schlag, PM ;
Moesta, KT .
APPLIED OPTICS, 1998, 37 (10) :1982-1989
[4]   Frequency-domain photon migration measurements of normal and malignant tissue optical properties in a human subject [J].
Fishkin, JB ;
Coquoz, O ;
Anderson, ER ;
Brenner, M ;
Tromberg, BJ .
APPLIED OPTICS, 1997, 36 (01) :10-20
[5]   Frequency-domain techniques enhance optical mammography: Initial clinical results [J].
Franceschini, MA ;
Moesta, KT ;
Fantini, S ;
Gaida, G ;
Gratton, E ;
Jess, H ;
Mantulin, WW ;
Seeber, M ;
Schlag, PM ;
Kaschke, M .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (12) :6468-6473
[6]  
GOLUB GH, 1973, SIAM REV, V15, P318, DOI 10.1137/1015032
[7]   Optical tomography breast imaging [J].
Grable, RJ ;
Rohler, DP .
OPTICAL TOMOGRAPHY AND SPECTROSCOPY OF TISSUE: THEORY, INSTRUMENTATION, MODEL, AND HUMAN STUDIES II, PROCEEDINGS OF, 1997, 2979 :197-210
[8]  
Guo PY, 2000, OSA TRENDS OPT PHOTO, V38, P97
[9]  
JHOLBOKE M, 2000, J BIOMED OPT, V5, P237
[10]   Optical image reconstruction using frequency-domain data: Simulations and experiments [J].
Jiang, HB ;
Paulsen, KD ;
Osterberg, UL ;
Pogue, BW ;
Patterson, MS .
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 1996, 13 (02) :253-266