Asymmetric synthesis of A-factor

被引：26

作者：

Crawforth, JM ^{[1
]}

Fawcett, J ^{[1
]}

Rawlings, BJ ^{[1
]}

机构：

[1] Univ Leicester, Dept Chem, Crystallog Sect, Leicester LE1 7RH, Leics, England

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1998年 / 10期

关键词：

D O I：

10.1039/a708638e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of enantiopure A-factor ['autoregulatory factor'; (3R)-(-)-2-(6-methylheptanoyl)-3-hydroxymethylbutano-4-lactone] by the completely diastereoselective benzyloxymethylation of (4R)-3-(3-phenylpropanoyl)-4-isopropyloxazolidin-2-one is reported.

引用

页码：1721 / 1725

页数：5

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