Invasive forms of Toxoplasma gondii, Leishmania amazonensis and Trypanosoma cruzi have a positive charge at their contact site with host cells

被引：12

作者：

Akaki, M

Nakano, Y

Nagayasu, E

Nagakura, K

Kawai, S

Aikawa, M ^{[1
]}

机构：

[1] Tokai Univ, Res Inst Sci & Technol, Kanagawa 2591193, Japan

[2] Tokai Univ, Dept Infect Dis, Sch Med, Kanagawa 2591193, Japan

[3] Dokkyo Univ, Sch Med, Dept Med Zool, Mibu, Tochigi 3210293, Japan

来源：

PARASITOLOGY RESEARCH | 2001年 / 87卷 / 03期

关键词：

D O I：

10.1007/PL00008574

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

We examined the surface charges of invasive forms of Toxoplasma gondii, Leishmania amazonensis, and Trypanosoma cruzi by atomic force microscopy and surface potential spectroscopy. We found that the specific part of the protozoan which makes initial contact with the host cell is positively charged. This indicates that the positive charge at the site of contact facilitates binding of the invasive protozoan to negatively charged host cells.

引用

页码：193 / 197

页数：5

共 24 条

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