Cytological evidence for association of the ends of the linear chromosome in Streptomyces coelicolor

被引：31

作者：

Yang, MC ^{[1
]}

Losick, R ^{[1
]}

机构：

[1] Harvard Univ, Dept Mol & Cellular Biol, Cambridge, MA 02138 USA

来源：

JOURNAL OF BACTERIOLOGY | 2001年 / 183卷 / 17期

关键词：

D O I：

10.1128/JB.183.17.5180-5186.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The chromosome of the filamentous bacterium Streptomyces coelicolor is linear, but the genetic map is circular. We present cytological evidence based on the use of fluorescence in situ hybridization showing that the ends of the chromosome frequently colocalize, in agreement with the idea that the ends are held together, effectively forming a circular chromosome. These observations provide a possible explanation for how a linear bacterial chromosome can exhibit a circular genetic map.

引用

页码：5180 / 5186

页数：7

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