Chiral recognition by molecularly imprinted polymers in aqueous media

被引:48
作者
Ramström, O [1 ]
Ye, L [1 ]
Gustavsson, PE [1 ]
机构
[1] Lund Univ, Ctr Chem & Chem Engn, S-22100 Lund, Sweden
关键词
column liquid chromatography; molecular imprinting; molecular recognition; chiral recognition;
D O I
10.1007/BF02467671
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Molecularly imprinted polymers were prepared using 2-vinylpyridine and/or methacrylic acid as functional monomers in a self-assembly imprinting protocol. The resulting polymers were analyzed in aqueous media, and the effects from the pH of the mobile phase and the degree of added organic solvent were investigated. The results are indicative of the importance of ionic bonds in conjunction with hydrophobic interactions in the formation of the complexes between the analyte and the polymers.
引用
收藏
页码:197 / 202
页数:6
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