Nicotine lowers the body-weight set-point in male rats

被引：35

作者：

Frankham, P ^{[1
]}

Cabanac, M ^{[1
]}

机构：

[1] Univ Laval, Fac Med, Dept Physiol, Quebec City, PQ G1K 7P4, Canada

来源：

APPETITE | 2003年 / 41卷 / 01期

基金：

加拿大自然科学与工程研究理事会;

关键词：

food hoarding; set point; body weight; ponderostat;

D O I：

10.1016/S0195-6663(03)00024-2

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Set-point of body weight was assessed by the behavioral method of the weight threshold to hoard food. Intra-peritoneal injection of nicotine (0.02-0.05 mg/kg) significantly lowered the rats' body weight set-point by 8.5 +/- 2.7 and 19.2 +/- 2.6 g (p less than or equal to 0.05). These results suggest that the administration of low-dose nicotine lowers the body-weight set-point and may be important in predicting the anticipated gain in weight frequently reported upon withdrawal. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：1 / 5

页数：5

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