Planar integrated optical methods for examining thin films and their surface adlayers

被引：39

作者：

Plowman, TE

Saavedra, SS

Reichert, WM ^{[1
]}

机构：

[1] Duke Univ, Dept Biomed Engn, Ctr Emerging Cardiovasc Technol, Durham, NC 27708 USA

[2] Univ Arizona, Dept Chem, Tucson, AZ 85721 USA

来源：

BIOMATERIALS | 1998年 / 19卷 / 4-5期

关键词：

optical waveguide; attenuated total reflection; waveguide Raman spectroscopy; fluoroimmunoassay; review;

D O I：

10.1016/S0142-9612(97)00113-0

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Thin film integrated optical waveguides (IOWs) have gained acceptance as a method for characterizing ultrathin dielectrical films and adlayers bound to the film surface. Here, we present the expressions that govern IOW methods as well as describe the common experimental configurations used in attenuated total reflection, fluorescence and Raman applications. The applications of these techniques to the study of adsorbed or surface-bound proteins to polymer and glass waveguides are reviewed. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：341 / 355

页数：15

共 85 条

[1] IMMUNOSENSORS FOR CLINICAL ANALYSIS [J].