The prognosis of gastric cardia cancer after R0 resection

被引：33

作者：

An, Ji Yeong ^{[2
]}

Baik, Yong Hae ^{[3
]}

Choi, Min Gew ^{[1
]}

Noh, Jae Hyung ^{[1
]}

Sohn, Tae Sung ^{[1
]}

Bae, Jae Moon ^{[1
]}

Kim, Sung ^{[1
]}

机构：

[1] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Surg, Seoul, South Korea

[2] Yonsei Univ, Coll Med, Dept Surg, Seoul, South Korea

[3] Dongguk Univ, Ilsan Hosp, Dept Surg, Goyang, South Korea

来源：

AMERICAN JOURNAL OF SURGERY | 2010年 / 199卷 / 06期

关键词：

Esophagogastric junction; Cardia; Gastric cancer; Prognosis; Surgery; GASTROESOPHAGEAL JUNCTION; ADENOCARCINOMA; RECURRENCE; MANAGEMENT; CARCINOMA; REGIONS; PATTERN; MARGIN;

D O I：

10.1016/j.amjsurg.2009.04.012

中图分类号：

R61 [外科手术学];

学科分类号：

100210 [外科学];

摘要：

BACKGROUND: The aim of this study was to evaluate the prognosis of gastric cardia cancers in comparison with other gastric cancers. METHODS: The medical records of 251 patients with gastric cardia cancers and 6568 patients with other gastric cancers who underwent R0 resection were reviewed. Clinicopathologic characteristics and survival were analyzed. RESULTS: Gastric cardia cancer was associated with more advanced staging and less favorable clinicopathologic features at diagnosis compared with other gastric cancers. The overall 5-year survival rates were 79.7% and 84.6% in patients with cardia cancer and other cancers, respectively. There were no significant differences in survival curves between the groups at any stage. Lymph node metastasis was an independent prognostic factor for disease-free survival. The length of the proximal margin was not associated with locoregional tumor recurrence. CONCLUSIONS: Although patients with gastric cardia cancers are diagnosed at an advanced stage, the long-term survival rates are similar to those with other gastric cancers. If curative resection with negative resection margin can be achieved, pN category is the only prognostic factor for survival. (C) 2010 Elsevier Inc. All rights reserved.

引用

页码：725 / 729

页数：5

共 12 条

[1]

Adenocarcinoma of the gastroesophageal junction - Influence of esophageal resection margin and operative approach on outcome [J].

Barbour, Andrew P. ;

Rizk, Nabil P. ;

Gonen, Mithat ;

Tang, Laura ;

Bains, Manjit S. ;

Rusch, Valerie W. ;

Coit, Daniel G. ;

Brennan, Murray F. .

ANNALS OF SURGERY, 2007, 246 (01) :1-8

[2]

Prognostic impact of resection margin involvement after extended (D2/D3) gastrectomy for advanced gastric cancer: A 15-year expereince at a single institute [J].

Cho, Byoung Chul ;

Jeung, Hei Cheul ;

Choi, Hye Jin ;

Rha, Sun Young ;

Hyung, Woo Jin ;

Cheong, Jae Ho ;

Noh, Sung Hoon ;

Chung, Hyun Cheol .

JOURNAL OF SURGICAL ONCOLOGY, 2007, 95 (06) :461-468

[3]

Pattern of recurrence after surgery in adenocarcinoma of the gastro-oesophageal junction [J].

de Manzoni, G ;

Pedrazzani, C ;

Pasini, F ;

Durante, E ;

Gabbani, M ;

Grandinetti, A ;

Guglielmi, A ;

Griso, C ;

Cordiano, C .

EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 2003, 29 (06) :506-510

[4]

Adenocarcinoma of the gastric cardia: What is the optimal surgical approach? [J].

Ito, H ;

Clancy, TE ;

Osteen, RT ;

Swanson, RS ;

Bueno, R ;

Sugarbaker, DJ ;

Ashley, SW ;

Zinner, MJ ;

Whang, EE .

JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2004, 199 (06) :880-886

[5]

Kim HJ, 2004, J KOREAN GASTRIC CAN, V4, P143

[6]

Extent of oesophageal adenocarcinorna of the resection for oesophagogastric junction [J].

Mariette, C ;

Castel, B ;

Balon, JM ;

Van Seuningen, I ;

Triboulet, JR .

EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 2003, 29 (07) :588-593

[7]

Surgical management of and long-term survival after adenocarcinoma of the cardia [J].

Mariette, C ;

Castel, B ;

Toursel, H ;

Fabre, S ;

Balon, JM ;

Triboulet, JP .

BRITISH JOURNAL OF SURGERY, 2002, 89 (09) :1156-1163

[8]

OHNO S, 1995, J AM COLL SURGEONS, V180, P577

[9]

Distinct recurrence pattern and outcome of adenocarcinoma of the gastric cardia in comparison with carcinoma of other regions of the stomach [J].

Saito, Hiroaki ;

Fukumoto, Youji ;

Osaki, Tomohiro ;

Fukuda, Kenji ;

Tatebe, Shigeru ;

Tsujitani, Shunichi ;

Ikeguchi, Masahide .

WORLD JOURNAL OF SURGERY, 2006, 30 (10) :1864-1869

[10]

Siewert JR, 2000, ANN SURG, V232, P353

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