Highly stereoselective cobalt-catalyzed allylation of functionalized diarylzinc reagents

被引：16

作者：

Dunet, Guillaume ^{[1
]}

Knochel, Paul ^{[1
]}

机构：

[1] Univ Munich, Dept Chem & Biochem, D-81377 Munich, Germany

来源：

SYNLETT | 2007年 / 09期

关键词：

catalysis; allylation; cobalt catalysis; organozinc reagents; stereoselective cross-coupling; nocarasin C;

D O I：

10.1055/s-2007-980344

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Functionalized diarylzinc reagents react readily with allylic chlorides or phosphates in the presence of Co(acac)(2) (10 mol%) to give the S(N)2 products in high yields and with retention of the double-bond configuration. Functionalities like ester, ketone, or cyano are tolerated.

引用

页码：1383 / 1386

页数：4

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