The possibility of eliminating blinding trachoma

被引:33
作者
Mecaskey, JW
Knirsch, CA
Kumaresan, JA
Cook, JA
机构
[1] Int Trachoma Initiat, New York, NY 10017 USA
[2] Pfizer Inc, New York, NY USA
[3] Columbia Univ, New York, NY USA
关键词
D O I
10.1016/S1473-3099(03)00807-7
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Global elimination of blinding trachoma, the world's leading preventable cause of blindness, now seems possible. The disease, which severely in the poorest persists most parts of Africa and Asia, is already eliminated in North America and Europe. On a scientific basis, the case for elimination was outlined at a WHO global scientific meeting in 1996. To facilitate action, WHO founded the Alliance for Global Elimination of Trachoma by 2020 (GET 2020) in 1997. In 1998 a World Health Assembly resolution called for member states to WHO documented trachoma countries take steps to eliminate blinding trachoma by 2020 using the WHO recommended SAFE strategy (surgery of late stage disease, antibiotics for acute infection, and improved facial hygiene and environmental change-ie, improved access to water and sanitation). These developments contributed to the decision by Pfizer Inc to donate azithromycin in support of national programmes implementing SAFE and, with the Edna McConnell Clark Foundation, to found the International Trachoma Initiative as a charity dedicated to the elimination of blinding trachoma by 2020. Reports of the early programme scope and impact are encouraging. In ten national programmes currently underway (constituting about 50% of the global burden) more than 55 000 lid surgeries have halted further corneal damage and prevented blindness, and more than 6 million treatments with azithromycin have been given with reductions in acute infections of around 50% in children. Morocco, one of the first countries to implement SAFE with azithromycin, has achieved remarkable results and expects to eliminate blinding trachoma by 2005. If political will and public-health support can be mobilised, the goal of eliminating this cause of blindness can become a reality by 2020.
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页码:728 / 734
页数:7
相关论文
共 52 条
  • [31] Trachoma
    Mabey, DCW
    Solomon, AW
    Foster, A
    [J]. LANCET, 2003, 362 (9379) : 223 - 229
  • [32] EXTRA-OCULAR INFECTIONS IN CHILDREN IN AREAS WITH ENDEMIC TRACHOMA
    MALATY, R
    ZAKI, S
    SAID, ME
    VASTINE, DW
    DAWSON, CR
    SCHACHTER, J
    [J]. JOURNAL OF INFECTIOUS DISEASES, 1981, 143 (06) : 853 - 853
  • [33] The eyes have it: Trachoma, the perception of disease, the United States public health service, and the American Jewish immigration experience, 1897-1924
    Markel, H
    [J]. BULLETIN OF THE HISTORY OF MEDICINE, 2000, 74 (03) : 525 - 560
  • [34] CHANGING WATER-USE PATTERNS IN A WATER-POOR AREA - LESSONS FOR A TRACHOMA INTERVENTION PROJECT
    MCCAULEY, AP
    LYNCH, M
    POUNDS, MB
    WEST, S
    [J]. SOCIAL SCIENCE & MEDICINE, 1990, 31 (11) : 1233 - 1238
  • [35] Antibiotic dosage in trachoma control programs:: Height as a surrogate for weight in children
    Muñoz, B
    Solomon, AW
    Zingeser, J
    Barwick, R
    Burton, M
    Bailey, R
    Mabey, D
    Foster, A
    West, SK
    [J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2003, 44 (04) : 1464 - 1469
  • [36] PROST A, 1989, B WORLD HEALTH ORGAN, V67, P9
  • [37] Reacher M H, 1990, Rev Int Trach Pathol Ocul Trop Subtrop Sante Publique, V67, P233
  • [38] A CONTROLLED TRIAL OF SURGERY FOR TRACHOMATOUS TRICHIASIS OF THE UPPER LID
    REACHER, MH
    MUNOZ, B
    ALGHASSANY, A
    DAAR, AS
    ELBUALY, M
    TAYLOR, HR
    [J]. ARCHIVES OF OPHTHALMOLOGY, 1992, 110 (05) : 667 - 674
  • [39] REACHER MH, 1993, WHOPBL9329
  • [40] EFFECTS OF AZITHROMYCIN ON MALARIOMETRIC INDEXES IN THE GAMBIA
    SADIQ, ST
    GLASGOW, KW
    DRAKELEY, CJ
    MULLER, O
    GREENWOOD, BM
    MABEY, DCW
    BAILEY, RL
    [J]. LANCET, 1995, 346 (8979): : 881 - 882