Risk factors for pulmonary arterial hypertension

被引:84
作者
Humbert, M [1 ]
Nunes, H [1 ]
Sitbon, O [1 ]
Parent, F [1 ]
Hervé, P [1 ]
Simonneau, G [1 ]
机构
[1] Univ Paris Sud, Ctr Maladies Vasc Pulm, Serv Pneumol & Reanimat Resp, Hop Antoine Beclere, F-92140 Clamart, France
关键词
D O I
10.1016/S0272-5231(05)70284-7
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Several risk factors for pulmonary arterial hypertension have been recognized including drugs and toxins, demographic and medical conditions, and diseases. Conclusions regarding the causal relationship between risk factors and the development of pulmonary hypertension relate to the magnitude of the association, the temporality of the association, and consistency of the observations. The exact mechanism(s) by which the risk factors produce pulmonary hypertension has not been established yet. Given the fact that the absolute risk is generally low, factors of individual susceptibility are likely to play an important role.
引用
收藏
页码:459 / +
页数:19
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