Pushing the Limits for Thiol-Ene and CuAAC Reactions: Synthesis of a 6th Generation Dendrimer in a Single Day

被引：152

作者：

Antoni, Per ^{[1
,2
,3
]}

Robb, Maxwell J. ^{[2
,3
]}

Campos, Luis ^{[2
,3
]}

Montanez, Maria ^{[1
]}

Hult, Anders ^{[1
]}

Malmstrom, Eva ^{[1
]}

Malkoch, Michael ^{[1
]}

Hawker, Craig J. ^{[2
,3
]}

机构：

[1] Royal Inst Technol, Sch Chem & Chem Sci, Div Coating Technol, S-10044 Stockholm, Sweden

[2] Univ Calif Santa Barbara, Dept Chem & Biochem, Dept Mat, Santa Barbara, CA 93106 USA

[3] Univ Calif Santa Barbara, MRL, Santa Barbara, CA 93106 USA

来源：

MACROMOLECULES | 2010年 / 43卷 / 16期

基金：

瑞典研究理事会;

关键词：

BROMO CLICK CHEMISTRY; RAPID SYNTHESIS; 1,3-DIPOLAR CYCLOADDITIONS; BIFUNCTIONAL DENDRIMERS; RADICAL POLYMERIZATION; MATERIALS SCIENCE; TERMINAL ALKYNES; STAR POLYMERS; MACROMOLECULES; COPOLYMERS;

D O I：

10.1021/ma101242u

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Dendrimer synthesis should not be tedious and time-consuming. By utilizing an AB(2)-CD2 approach and having orthogonal, "clickable" groups on each monomer, the time for dendrimer assembly can be drastically reduced. This was shown by preparation of a sixth generation dendrimer from starting monomer units in a single day.

引用

页码：6625 / 6631

页数：7

共 45 条

[1]

Antoni P, 2007, CHEM COMMUN, P2249, DOI 10.1039/b703547k

[2] Bifunctional Dendrimers: From Robust Synthesis and Accelerated One-Pot Postfunctionalization Strategy to Potential Applications [J].

Antoni, Per ;

Hed, Yvonne ;

Nordberg, Axel ;

Nystrom, Daniel ;

von Holst, Hans ;

Hult, Anders ;

Malkoch, Michael .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (12) :2126-2130

[3] 'Click' chemistry in polymer and materials science [J].

Binder, Wolfgang H. ;

Sachsenhofer, Robert .

MACROMOLECULAR RAPID COMMUNICATIONS, 2007, 28 (01) :15-54

[4] High-throughput synthesis of nanoscale materials:: Structural optimization of functionalized one-step star polymers [J].

Bosman, AW ;

Heumann, A ;

Klaerner, G ;

Benoit, D ;

Fréchet, JMJ ;

Hawker, CJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (26) :6461-6462

[5] First divergent strategy using two AB2 unprotected monomers for the rapid synthesis of dendrimers [J].

Brauge, L ;

Magro, G ;

Caminade, AM ;

Majoral, JP .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (27) :6698-6699

[6]

BUHLEIER E, 1978, SYNTHESIS-STUTTGART, P155

[7] The Emergence of Thiol-Ene Coupling as a Click Process for Materials and Bioorganic Chemistry [J].

Dondoni, Alessandro .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2008, 47 (47) :8995-8997

[8] MOLECULAR SIZE DISTRIBUTION IN THREE DIMENSIONAL POLYMERS .6. BRANCHED POLYMERS CONTAINING A-R-BF-1 TYPE UNITS [J].

FLORY, PJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1952, 74 (11) :2718-2723

[9] Pyrene Functional Poly(vinyl alcohol) by "Click" Chemistry [J].

Gacal, Bahadir N. ;

Koz, Banu ;

Gacal, Burcin ;

Kiskan, Baris ;

Erdogan, Matem ;

Yagci, Yusuf .

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2009, 47 (05) :1317-1326

[10] Synthesis of Glyco-Microspheres via a Thiol-Ene Coupling Reaction [J].

Gu, Wenfang ;

Chen, Gaojian ;

Stenzel, Martina H. .

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2009, 47 (20) :5550-5556

← 1 2 3 4 5 →