Phthalimide resin reagent for efficient Mitsunobu amino-dehydroxylation

被引：27

作者：

Aronov, AM

Gelb, MH ^{[1
]}

机构：

[1] Univ Washington, Dept Chem, Seattle, WA 98195 USA

[2] Univ Washington, Dept Biochem, Seattle, WA 98195 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 28期

基金：

美国国家卫生研究院;

关键词：

nucleosides; amination; polymer support;

D O I：

10.1016/S0040-4039(98)00964-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A phthalimide-containing resin has been designed and prepared from trimellitic anhydride. It provides an efficient route to primary amines from corresponding alcohols via Mitsunobu coupling with subsequent hydrazine-induced cleavage. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：4947 / 4950

页数：4

共 9 条

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