Renierosides, Cerebrosides from a marine sponge Haliclona (Reniera) sp.

被引：34

作者：

Mansoor, Tayyab A.

Shinde, Pramod B.

Luo, Xuan

Hong, Jongki

Lee, Chong-O.

Sim, Chung Ja

Son, Byeng Wha

Jung, Jee H. ^{[1
]}

机构：

[1] Pusan Natl Univ, Coll Pharm, Pusan 609735, South Korea

[2] Kyung Hee Univ, Coll Pharm, Seoul 130701, South Korea

[3] Korea Res Inst Chem Technol, Taejon 305343, South Korea

[4] Hannam Univ, Taejon 306791, South Korea

[5] Pukyong Natl Univ, Basic Sci Res Inst, Pusan 608737, South Korea

[6] Univ Lisbon, Fac Farm, P-1600083 Lisbon, Portugal

来源：

JOURNAL OF NATURAL PRODUCTS | 2007年 / 70卷 / 09期

关键词：

D O I：

10.1021/np070078u

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Guided by the brine shrimp lethality assay, eight new cerebrosides (1-8) have been isolated from an extract of the marine sponge Haliclona (Reniera) sp. A novel feature of these cerebrosides was the presence of unprecedented amide-linked long-chain fatty acid moieties. The planar structures of the cerebrosides (1-8) were established by 1D and 2D NMR spectroscopic techniques, mass spectrometric analyses, and chemical degradation methods. The isolated compounds did not display cytotoxicity to a panel of five human solid tumor cell lines.

引用

页码：1481 / 1486

页数：6

共 22 条

[1]

PHOSPHOLIPID STUDIES OF MARINE ORGANISMS .4. (2R,21Z)-2-METHOXY-21-OCTACOSENOIC ACID, THE 1ST NATURALLY-OCCURRING ALPHA-METHOXY ACID FROM A PHOSPHOLIPID [J].