Nanomagnetic particles for SQUID-based magnetically labeled immunoassay

被引：38

作者：

Horng, HE ^{[1
]}

Yang, SY

Huang, YW

Jiang, WQ

Hong, CY

Yang, HC

机构：

[1] Natl Taiwan Normal Univ, Inst Electroopt Sci & Technol, Taipei 116, Taiwan

[2] Natl Taiwan Normal Univ, Dept Phys, Taipei 116, Taiwan

[3] Univ Sci & Technol China, Dept Chem, Hefei 230026, Peoples R China

[4] Da Yeh Univ, Dept Mech & Automat Engn, Changhua 515, Taiwan

[5] Natl Taiwan Univ, Dept Phys, Taipei 106, Taiwan

来源：

IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY | 2005年 / 15卷 / 02期

关键词：

immunoassay; nanomagnetic particles; SQUIDS;

D O I：

10.1109/TASC.2005.849995

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

With the increasing importance of SQUID-based magnetically labeled immunoassay, the study on the synthesis of controllable sizes of magnetic nanoparticles plays a role to promote the accuracy of the immunoassay. In this work, Fe3O4 nano-particles coated with a suitable bio-probe (biotin) are synthesized through chemical co-precipitation process to probe the bio-target (avidin). Through the synthesis developed here, the particle hydrodynamic diameter can be adjusted from 30 to 90 run, which provide candidates for probing various bio-targets in the future. The amount of the magnetically labeled avidin is then analyzed via measuring the saturated magnetization or the remanence of the sample by using a SQUID magnetometer.

引用

页码：668 / 671

页数：4