Aggregation-enhanced fluorescence in organically modified silica nanoparticles: A novel approach toward high-signal-output nanoprobes for two-photon fluorescence bioimaging

被引:185
作者
Kim, Sehoon [1 ]
Pudavar, Haridas E. [1 ]
Bonoiu, Adela [1 ]
Prasad, Paras N. [1 ]
机构
[1] SUNY Buffalo, Inst Laser Photon & Biophoton, Dept Chem, Buffalo, NY 14260 USA
关键词
OPTICAL-DATA STORAGE; DRUG-CARRIER; ABSORPTION; MICROSCOPY; DYE; PARTICLES; READOUT; SURFACE;
D O I
10.1002/adma.200700098
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Phase-separated nanoaggregation of a highly loaded 9,10-bis[4'-(4"-aminostyryl)styryl]anthracene dye in organically modified silica (ORMOSIL) nanoparticles boosts intracellular two-photon fluorescence signal by virtue of enhanced two-photon absorption and emission, high chromophore number density in the nano-space, and noninvasive cellular uptake.
引用
收藏
页码:3791 / +
页数:6
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