Isoxazoline derivatives from activated primary nitrocompounds and tertiary diamines

被引：42

作者：

Cecchi, L

De Sarlo, F

Machetti, F

机构：

[1] Univ Florence, Dipartimento Chim Organ U Schiff, I-50019 Florence, Italy

[2] CNR, Dipartimento Chim Organ U Schiff, Ist Chim Composti Organo Met, I-50019 Florence, Italy

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 46期

关键词：

isoxazolines; nitroalkanes; diamines;

D O I：

10.1016/j.tetlet.2005.09.110

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Activated nitrocompounds, in the presence of dipolarophiles and a tertiary diamine (e.g., DABCO), undergo dehydration to afford directly isoxazoline derivatives, formal cycloadducts of nitrile oxides; this mild procedure is very efficient for the synthesis of the reported isoxazolines. (c) 2005 Elsevier Ltd. All rights reserved.

引用

收藏

页码：7877 / 7879

页数：3

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