Programming of Erythromycin Biosynthesis by a Modular Polyketide Synthase

被引:52
作者
Cane, David E. [1 ]
机构
[1] Brown Univ, Dept Chem, Providence, RI 02912 USA
基金
美国国家卫生研究院;
关键词
ACYL CARRIER PROTEIN; FATTY-ACID SYNTHASE; BETA-KETOREDUCTASE DOMAINS; 6-DEOXYERYTHRONOLIDE-B SYNTHASE; SACCHAROPOLYSPORA-ERYTHRAEA; CRYSTAL-STRUCTURE; INTERMODULAR COMMUNICATION; MECHANISTIC ANALYSIS; 4-PRO-S HYDRIDE; MOLECULAR-BASIS;
D O I
10.1074/jbc.R110.144618
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:27517 / 27523
页数:7
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