Next Generation Radiologic-Pathologic Correlation in Oncology: Rad-Path 2.0

被引：27

作者：

Kuo, Michael D. ^{[1
,2
,3
]}

Yamamoto, Shota ^{[1
,3
]}

机构：

[1] Univ Calif Los Angeles, David Geffen Sch Med, Dept Radiol Sci, Los Angeles, CA 90095 USA

[2] Univ Calif Los Angeles, David Geffen Sch Med, Dept Pathol, Los Angeles, CA 90095 USA

[3] Univ Calif Los Angeles, David Geffen Sch Med, Radiol Pathol Program, Los Angeles, CA 90095 USA

来源：

AMERICAN JOURNAL OF ROENTGENOLOGY | 2011年 / 197卷 / 04期

关键词：

histopathologic findings; molecular imaging; radiologic findings; radiogenomics; radiologic-pathologic correlation; B-CELL LYMPHOMA; GENE-EXPRESSION PROFILES; UNRESECTABLE HEPATOCELLULAR-CARCINOMA; POSITRON-EMISSION-TOMOGRAPHY; HER2-POSITIVE BREAST-CANCER; LUNG-CANCER; GLIOBLASTOMA-MULTIFORME; ADJUVANT CHEMOTHERAPY; MOLECULAR SUBTYPES; PREDICT SURVIVAL;

D O I：

10.2214/AJR.11.7163

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

OBJECTIVE. The bedrock of radiology has been radiologic-pathologic (Rad-Path) correlation: the correlation of imaging to ex vivo gross and histopathologic findings of disease. This classical view is being challenged by our increasing understanding of the molecular basis of disease, particularly in oncology. The traditional lines in diagnostic sciences have blurred with the development of new in vitro diagnostic molecular assays and molecular imaging methods as well as the growing evidence that conventional diagnostic imaging has potential use in understanding genomic properties of disease. The purpose of this article is to make the case for a fundamental shift to the next generation of Rad-Path correlation (Rad-Path 2.0). CONCLUSION. The future success of radiology will require not only continued technologic advances in physical and life sciences but also the convergence of previously distinct diagnostic disciplines.

引用

页码：990 / 997

页数：8

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