Nitric oxide synthase gene transfer to the vessel wall

被引:13
作者
Kibbe, M [1 ]
Billiar, T [1 ]
Tzeng, E [1 ]
机构
[1] Univ Pittsburgh, Dept Surg, Pittsburgh, PA 15261 USA
关键词
D O I
10.1097/00041552-199901000-00012
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
A wide array of vascular disorders have been shown to benefit from gene therapy. Given the vasoprotective role that nitric oxide plays in the vasculature, it is understandable why gene therapy with the three different isoforms of nitric oxide synthase has been so successful. This review summarizes the current literature pertaining to nitric oxide synthase gene transfer to the vascular wall. Curr Opin Nephrol Hypertens 8:75-81. (C) 1999 Lippincott Williams & Wilkins.
引用
收藏
页码:75 / 81
页数:7
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