Nitric oxide synthase gene transfer to the vessel wall

被引：13

作者：

Kibbe, M ^{[1
]}

Billiar, T ^{[1
]}

Tzeng, E ^{[1
]}

机构：

[1] Univ Pittsburgh, Dept Surg, Pittsburgh, PA 15261 USA

来源：

CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION | 1999年 / 8卷 / 01期

关键词：

D O I：

10.1097/00041552-199901000-00012

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

A wide array of vascular disorders have been shown to benefit from gene therapy. Given the vasoprotective role that nitric oxide plays in the vasculature, it is understandable why gene therapy with the three different isoforms of nitric oxide synthase has been so successful. This review summarizes the current literature pertaining to nitric oxide synthase gene transfer to the vascular wall. Curr Opin Nephrol Hypertens 8:75-81. (C) 1999 Lippincott Williams & Wilkins.

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页码：75 / 81

页数：7

相关论文

共 47 条

[21] Enhanced endothelium-dependent relaxations after gene transfer of recombinant endothelial nitric oxide synthase to rabbit carotid arteries [J].

Kullo, IJ ;

Mozes, G ;

Schwartz, RS ;

Gloviczki, P ;

Tsutsui, M ;

Katusic, ZS ;

OBrien, T .

HYPERTENSION, 1997, 30 (03) :314-320

[22] Expression and function of recombinant endothelial NO synthase in coronary artery smooth muscle cells [J].

Kullo, IJ ;

Schwartz, RS ;

Pompili, VJ ;

Tsutsui, M ;

Milstien, S ;

Fitzpatrick, LA ;

Katusic, ZS ;

OBrien, T .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 1997, 17 (11) :2405-2412

[23] Prolonged reduction of high blood pressure with human nitric oxide synthase gene delivery [J].

Lin, KF ;

Chao, L ;

Chao, J .

HYPERTENSION, 1997, 30 (03) :307-313

[24] Hemagglutinating virus of Japan-liposome-mediated gene transfer of endothelial cell nitric oxide synthase inhibits intimal hyperplasia of canine vein grafts under conditions of poor runoff [J].

Matsumoto, T ;

Komori, K ;

Yonemitsu, Y ;

Morishita, R ;

Sueishi, K ;

Kaneda, Y ;

Sugimachi, K .

JOURNAL OF VASCULAR SURGERY, 1998, 27 (01) :135-144

[25]

MCQUILLAN LP, 1995, AM J PHYSL H, V268

[26]

MCQUILLAN LP, 1995, AM J PHYSL 3 H, V268

[27]

McQuillan Lynda P., 1994, American Journal of Physiology, V267, pH1921

[28]

MEHRA MR, 1995, TEX HEART I J, V22, P138

[29] Expression and function of recombinant endothelial nitric oxide synthase gene in canine basilar artery after experimental subarachnoid hemorrhage [J].

Onoue, H ;

Tsutsui, M ;

Smith, L ;

Stelter, A ;

O'Brien, T ;

Katusic, ZS .

STROKE, 1998, 29 (09) :1959-1965

[30] Altered vascular function after adenovirus-mediated overexpression of endothelial nitric oxide synthase [J].

Ooboshi, H ;

Chu, Y ;

Rios, CD ;

Faraci, FM ;

Davidson, BL ;

Heistad, DD .

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 1997, 273 (01) :H265-H270

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