Oxidative stress: A dead end or a laboratory hypothesis?

被引：48

作者：

Azzi, Angelo ^{[1
]}

机构：

[1] Tufts Univ, JM USDA HNRCA, Vasc Biol Lab, Boston, MA 02111 USA

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 2007年 / 362卷 / 02期

关键词：

oxidative stress; antioxidants; free radicals;

D O I：

10.1016/j.bbrc.2007.07.124

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Oxidative stress is a highly used definition. The relevance of this concept is discussed in the light of the questionable effects of antioxidants in vitro and in vivo. The description of local cellular sources of oxidants and radicals as pathophysiologically important in signaling suggests the need for a re-discussion of the holistic concept of oxidative stress. (C) 2007 Elsevier Inc. All rights reserved.

引用

页码：230 / 232

页数：3

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