TOUCAN 2: the all-inclusive open source workbench for regulatory sequence analysis

被引:110
作者
Aerts, S
Van Loo, P
Thijs, G
Mayer, H
de Martin, R
Moreau, Y
De Moor, B
机构
[1] Flanders Interuniv Inst Biotechnol, Dept Human Genet, Neurogenet Lab, B-3000 Louvain, Belgium
[2] Katholieke Univ Leuven, ESAT, SCD, Dept Elect Engn,Bioinformat Grp, Louvain, Belgium
[3] Med Univ Vienna, Ctr Biomol Med & Pharmacol, Dept Vasc Biol & Thrombosis Res, Vienna, Austria
[4] Biomol Therapeut, Vienna, Austria
关键词
D O I
10.1093/nar/gki354
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We present the second and improved release of the TOUCAN workbench for cis-regulatory sequence analysis. TOUCAN implements and integrates fast state-of-the-art methods and strategies in gene regulation bioinformatics, including algorithms for comparative genomics and for the detection of cis-regulatory modules. This second release of TOUCAN has become open source and thereby carries the potential to evolve rapidly. The main goal of TOUCAN is to allow a user to come to testable hypotheses regarding the regulation of a gene or of a set of co-regulated genes. TOUCAN can be launched from this location: http://www.esat.kuleuven.ac.be/similar to saerts/software/toucan.php.
引用
收藏
页码:W393 / W396
页数:4
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