FootPrinter: a program designed for phylogenetic footprinting

被引:121
作者
Blanchette, M
Tompa, M
机构
[1] Univ Washington, Dept Comp Sci & Engn, Seattle, WA 98195 USA
[2] Univ Calif Santa Cruz, Ctr Biomol Sci & Engn, Santa Cruz, CA 95064 USA
关键词
D O I
10.1093/nar/gkg606
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Phylogenetic footprinting is a method for the discovery of regulatory elements in a set of homologous regulatory regions, usually collected from multiple species. It does so by identifying the best conserved motifs in those homologous regions. This note describes web software that has been designed specifically for this purpose, making use of the phylogenetic relationships among the homologous sequences in order to make more accurate predictions. The software is called FootPrinter and is available at http://bio.cs.washington.edu/software.html.
引用
收藏
页码:3840 / 3842
页数:3
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