A very efficient synthesis of a mannosyl orthoester [2]rotaxane and mannosidic [2]rotaxanes

被引：30

作者：

Coutrot, Frederic ^{[1
]}

Busseron, Eric

Montero, Jean-Louis

机构：

[1] Univ Montpellier 2, UMR CNRS 5247, IBMM, Ecole Natl Super Chim Montpellier, F-34296 Montpellier 5, France

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 05期

关键词：

D O I：

10.1021/ol702779z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The direct preparation of mannosyl[2]rotaxane derivatives by O-glycosylation from tetra-O-acetyl-alpha-D-mannosyltrichloroacetimidate and a tert-butylanilinium alcohol in the presence of dibenzo-24-crown-8 is described. The method appears to be very efficient and allows for the preparation of either orthoester or mannosyl rotaxane derivatives, depending on reaction conditions.

引用

页码：753 / 756

页数：4