Temperature distribution as function of time around a small spherical heat source of local magnetic hyperthermia

被引：172

作者：

Andrä, W

d'Ambly, CG

Hergt, R

Hilger, I

Kaiser, WA

机构：

[1] Inst Phys Hochtechnol EV, D-07743 Jena, Germany

[2] Univ Jena Klinikum, Inst Diagnost & Intervent Radiol, D-07740 Jena, Germany

来源：

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 1999年 / 194卷 / 1-3期

关键词：

hyperthermia; localized heat source; heat conduction simulation; breast carcinoma;

D O I：

10.1016/S0304-8853(98)00552-6

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

A spherical region containing magnetic particles embedded in extended muscle tissue is taken as model of small breast carcinomas. Using analytically derived equations the spatial temperature distribution is calculated as function of the time for exposing to an alternating magnetic field. In vitro measurements with muscle tissue yielded such an agreement with the calculations that treatment of small tumors in slightly vascularized tissues on the base of mathematical predictions seems now to be more promising than in the past. (C) 1999 Published by Elsevier Science B.V. All rights reserved.

引用

页码：197 / 203

页数：7

共 18 条

[1]

Abramowitz M., 1970, HDB MATH FUNCTIONS

[2]

[Anonymous], 1998, MAGNETISM MED

[3]

Brezovich I.A., 1988, MED PHYSICS MONOGRAP, V16, P82

[4]

BUTTON T, 1996, Patent No. 5492122

[5]

Carslaw H.S., 1967, Conduction of Heat in Solids

[6]

CHAN DCF, 1997, SCI CLIN APPL MAGNET

[7] 3-DIMENSIONAL SIMULATIONS OF FERROMAGNETIC IMPLANT HYPERTHERMIA [J].

CHEN, ZP ;

ROEMER, RB ;

CETAS, TC .

MEDICAL PHYSICS, 1992, 19 (04) :989-997

[8] THE EFFECTS OF LARGE BLOOD-VESSELS ON TEMPERATURE DISTRIBUTIONS DURING SIMULATED HYPERTHERMIA [J].

CHEN, ZP ;

ROEMER, RB .

JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 1992, 114 (04) :473-481

[9] SELECTIVE INDUCTIVE HEATING OF LYMPH NODES [J].

GILCHRIST, RK ;

MEDAL, R ;

SHOREY, WD ;

HANSELMAN, RC ;

PARROTT, JC ;

TAYLOR, CB .

ANNALS OF SURGERY, 1957, 146 (04) :596-606

[10] Physical limits of hyperthermia using magnetite fine particles [J].

Hergt, R ;

Andra, W ;

d'Ambly, CG ;

Hilger, I ;

Kaiser, WA ;

Richter, U ;

Schmidt, HG .

IEEE TRANSACTIONS ON MAGNETICS, 1998, 34 (05) :3745-3754

← 1 2 →