Innovative proteomic approaches for cancer biomarker discovery

被引：27

作者：

Faca, Vitor ^{[1
]}

Krasnoselsky, Alexei ^{[1
]}

Hanash, Samir ^{[1
]}

机构：

[1] Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 USA

来源：

BIOTECHNIQUES | 2007年 / 43卷 / 03期

关键词：

D O I：

10.2144/000112541

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Substantial technological advances in proteomics and related computational science have been made in the past few years. These advances overcome in part the complexity and heterogeneity of the human proteome, permitting quantitative analysis and identification of protein changes associated with tumor development. Here, we discuss some of these advances that are uncovering new cancer biomarkers that have potential to detect cancer at early and curable stages and address remaining challenges.

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页码：279 / +

页数：5

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