Synthesis and evaluation of caffeic acid amides as antioxidants

被引：135

作者：

Rajan, P

Vedernikova, I

Cos, P

Vanden Berghe, D

Augustyns, K

Haemers, A

机构：

[1] Univ Instelling Antwerp, Dept Med Chem, B-2610 Antwerp, Belgium

[2] Univ Instelling Antwerp, Dept Pharmaceut Microbiol, B-2610 Antwerp, Belgium

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2001年 / 11卷 / 02期

关键词：

D O I：

10.1016/S0960-894X(00)00630-2

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A series of amides of caffeic acid has been synthesised and their antioxidant properties evaluated as lipid peroxidation inhibitors. Anilides of caffeic acid were found to be very efficient antioxidants with IC50's Of 0.3 muM. (C) 2001 Elsevier Science Ltd. All rights reserved.

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页码：215 / 217

页数：3

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