Innate immune defense against malaria infection in the mosquito

被引:104
作者
Dimopoulos, G [1 ]
Müller, HM [1 ]
Levashina, EA [1 ]
Kafatos, FC [1 ]
机构
[1] European Mol Biol Lab, D-69117 Heidelberg, Germany
基金
美国国家卫生研究院;
关键词
D O I
10.1016/S0952-7915(00)00186-2
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Anopheles gambiae, the most important vector of malaria, employs its innate immune system in the light against Plasmodium. This can affect the propagative capacity of Plasmodium in the vector and, in some cases, leads to total refractoriness to the parasite. The components operating in the mosquito's innate immune system and their potential relevance to antimalarial responses are being systematically dissected.
引用
收藏
页码:79 / 88
页数:10
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