Quality of life and voice in patients with laryngeal carcinoma:: A posttreatment comparison of laryngectomy (Salvage surgery) versus radiotherapy

被引:66
作者
Finizia, C [1 ]
Hammerlid, E [1 ]
Westin, T [1 ]
Lindström, J [1 ]
机构
[1] Gothenburg Univ, Sahlgrens Hosp, Dept Otolaryngol Head & Neck Surg, S-41345 Gothenburg, Sweden
关键词
D O I
10.1097/00005537-199810000-00027
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Objectives: This study was designed 60 compare the voice and the quality of life (QOL) of laryngeal cancer patients receiving treatment with radical radiotherapy with or without laryngectomy as salvage surgery. We also compared the patients' own perceptual ratings of their voice to the perceptual ratings of a group of listeners. Study Design: Two groups of laryngeal cancer patients were studied. Methods: Fourteen irradiated laryngeal speakers with preserved larynx were matched with 14 salvage surgery laryngectomized patients speaking with tracheoesophageal prosthesis (TEP). To measure patients' QOL, we used the European Organisation for Research and Treatment of Cancer Quality of Life Core Questionnaire (EORTC QLQ-C30), the EORTC Head and Neck module (EORTC QLQ-H&N35), the Hospital Anxiety and Depression scale (HAD) and a study-specific questionnaire. For the perceptual speech evaluation we used visual analog scales. Results: The perceptual ratings of speech intelligibility, voice quality, and speech acceptability showed a significant difference between the treatment groups. Both the patients who received treatment with radiotherapy and the listeners rated the irradiated laryngeal voices higher than the tracheoesophageal speech. The laryngectomized patients scored significantly better than the patients treated with radical radiotherapy on the question about hoarseness. No other significant difference was found for the QOL functions and symp toms. Conclusion: When patients treated with radiotherapy were compared with patients treated with laryngectomy as salvage surgery, QOL was similar, only small differences being found in the perceptual speech evaluation.
引用
收藏
页码:1566 / 1573
页数:8
相关论文
共 49 条
[1]   THE EUROPEAN-ORGANIZATION-FOR-RESEARCH-AND-TREATMENT-OF-CANCER QLQ-C30 - A QUALITY-OF-LIFE INSTRUMENT FOR USE IN INTERNATIONAL CLINICAL-TRIALS IN ONCOLOGY [J].
AARONSON, NK ;
AHMEDZAI, S ;
BERGMAN, B ;
BULLINGER, M ;
CULL, A ;
DUEZ, NJ ;
FILIBERTI, A ;
FLECHTNER, H ;
FLEISHMAN, SB ;
DEHAES, JCJM ;
KAASA, S ;
KLEE, M ;
OSOBA, D ;
RAZAVI, D ;
ROFE, PB ;
SCHRAUB, S ;
SNEEUW, K ;
SULLIVAN, M ;
TAKEDA, F .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1993, 85 (05) :365-376
[2]   COMMUNICATION, FUNCTIONAL-DISORDERS AND LIFE-STYLE CHANGES AFTER TOTAL LARYNGECTOMY [J].
ACKERSTAFF, AH ;
HILGERS, FJM ;
AARONSON, NK ;
BALM, AJM .
CLINICAL OTOLARYNGOLOGY, 1994, 19 (04) :295-300
[3]   THE EORTC QLQ-LC13 - A MODULAR SUPPLEMENT TO THE EORTC CORE QUALITY-OF-LIFE QUESTIONNAIRE (QLQ-C30) FOR USE IN LUNG-CANCER CLINICAL-TRIALS [J].
BERGMAN, B ;
AARONSON, NK ;
AHMEDZAI, S ;
KAASA, S ;
SULLIVAN, M .
EUROPEAN JOURNAL OF CANCER, 1994, 30A (05) :635-642
[4]   PSYCHOMETRIC VALIDATION OF THE EORTC CORE QUALITY-OF-LIFE QUESTIONNAIRE, 30-ITEM VERSION AND A DIAGNOSIS-SPECIFIC MODULE FOR HEAD AND NECK-CANCER PATIENTS [J].
BJORDAL, K ;
KAASA, S .
ACTA ONCOLOGICA, 1992, 31 (03) :311-321
[5]   QUALITY-OF-LIFE IN PATIENTS TREATED FOR HEAD AND NECK-CANCER - A FOLLOW-UP-STUDY 7 TO 11 YEARS AFTER RADIOTHERAPY [J].
BJORDAL, K ;
KAASA, S ;
MASTEKAASA, A .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1994, 28 (04) :847-856
[6]   DEVELOPMENT OF A EUROPEAN-ORGANIZATION-FOR-RESEARCH-AND-TREATMENT-OF-CANCER (EORTC) QUESTIONNAIRE MODULE TO BE USED IN QUALITY-OF-LIFE ASSESSMENTS IN HEAD AND NECK-CANCER PATIENTS [J].
BJORDAL, K ;
AHLNERELMQVIST, M ;
TOLLESSON, E ;
JENSEN, AB ;
RAZAVI, D ;
MAHER, EJ ;
KAASA, S .
ACTA ONCOLOGICA, 1994, 33 (08) :879-885
[7]  
Blood GW., 1992, AM J SPEECH-LANG PAT, V1, P63, DOI [10.1044/1058-0360.0102.63, DOI 10.1044/1058-0360.0102.63]
[8]  
Bradley J. V., 1968, DISTRIBUTION FREE ST, P78
[9]  
Bradley JV, 1968, DISTRIBUTION FREE ST, P76
[10]   PSYCHOLOGICAL REACTIONS IN PATIENTS WITH MALIGNANT-MELANOMA [J].
BRANDBERG, Y ;
MANSSONBRAHME, E ;
RINGBORG, U ;
SJODEN, PO .
EUROPEAN JOURNAL OF CANCER, 1995, 31A (02) :157-162