Large scale domain movement in cytochrome bc1:: a new device for electron transfer in proteins

被引:119
作者
Darrouzet, E
Moser, CC
Dutton, PL
Daldal, F [1 ]
机构
[1] CEA VALRHO, DSV, DIEP, Serv Biochim Postgenom & Toxicol Nucl, F-30207 Bagnols Sur Ceze, France
[2] Univ Penn, Dept Biochem & Biophys, Johnson Res Fdn, Philadelphia, PA 19104 USA
[3] Univ Penn, Inst Plant Sci, Dept Biol, Philadelphia, PA 19104 USA
关键词
D O I
10.1016/S0968-0004(01)01897-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Recently, crystallographic, spectroscopic, kinetic and biochemical genetic data have merged to unveil a large domain movement for the Fe-S subunit in cytochrome be,. in this evolutionarily conserved enzyme, the domain motion acts to conduct intra-complex electron transfer and is essential for redox energy conversion.
引用
收藏
页码:445 / 451
页数:7
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