Cucurbitane-type triterpenoids from the stems of Momordica charantia

被引:63
作者
Chang, Chi-I [2 ]
Chen, Chiy-Rong [3 ]
Liao, Yun-Wen [2 ]
Cheng, Hsueh-Ling [2 ]
Chen, Yo-Chia [2 ]
Chou, Chang-Hung [1 ]
机构
[1] China Med Univ, Res Ctr Biodivers, Taichung 40402, Taiwan
[2] Natl Pingtung Univ Sci & Technol, Grad Inst Biotechnol, Pingtung 91201, Taiwan
[3] Meiho Inst Technol, Dept Biol Sci & Technol, Pingtung 91201, Taiwan
来源
JOURNAL OF NATURAL PRODUCTS | 2008年 / 71卷 / 08期
关键词
D O I
10.1021/np070532u
中图分类号
Q94 [植物学];
学科分类号
071001 [植物学];
摘要
Four new cucurbitane-type triterpenes, cucurbita-5,23(E)-diene-3 beta,7 beta,25-triol (1), 3 beta-acetoxy-7 beta-methoxycucurbita-5,23(E)-dien-25-ol (2), cucurbita-5(10),6,23(E)-triene-3 beta,25-diol (5), and cucurbita-5,24-diene-3,7,23-trione (6), together with four known triterpenes, 3 beta,25-dihydroxy-7 beta-methoxycucurbita-5,23(E)-diene (3), 3 beta-hydroxy-7 beta,25-dimethoxycucurbita-5,23(E)-diene (4), 3,7,25-trihydroxycucurbita-5,23(E-dien-19-al (7), and 25-methoxy-3 beta,7 beta-dillydroxycucurbita-5,23(E)-dien- 19-al (8), were isolated from the methyl alcohol extract of the stems of Momordica charantia. The structures of the new Compounds were elucidated by spectroscopic methods.
引用
收藏
页码:1327 / 1330
页数:4
相关论文
共 25 条
[1]
Cucurbitane-type triterpenoids from the fruits of Momordica charantia and their cancer chemopreventive effects [J].
Akihisa, Toshihiro ;
Higo, Naoki ;
Tokuda, Harukuni ;
Ukiya, Motohiko ;
Akazawa, Hiroyuki ;
Tochigi, Yuichi ;
Kimura, Yumiko ;
Suzuki, Takashi ;
Nishino, Hoyoku .
JOURNAL OF NATURAL PRODUCTS, 2007, 70 (08) :1233-1239
[2]
Triterpenes, a sterol and a monocyclic alcohol from Momordica charantia [J].
Begum, S ;
Ahmed, M ;
Siddiqui, BS ;
Khan, A ;
Saify, ZS ;
Arif, M .
PHYTOCHEMISTRY, 1997, 44 (07) :1313-1320
[3]
Cucurbitane-type triterpenoids from Momordica charantia [J].
Chang, Chi-I ;
Chen, Chiy-Rong ;
Liao, Yun-Wen ;
Cheng, Hsueh-Ling ;
Chen, Yo-Chia ;
Chou, Chang-Hung .
JOURNAL OF NATURAL PRODUCTS, 2006, 69 (08) :1168-1171
[4]
DUTTA PK, 1981, INDIAN J CHEM B, V20, P669
[5]
ELGENGAIHI S, 1995, PHARMAZIE, V50, P361
[6]
NEW CUCURBITANE TRITERPENOIDS FROM MOMORDICA-CHARANTIA [J].
FATOPE, MO ;
TAKEDA, Y ;
YAMASHITA, H ;
OKABE, H ;
YAMAUCHI, T .
JOURNAL OF NATURAL PRODUCTS, 1990, 53 (06) :1491-1497
[7]
ACYLGLUCOSYL STEROLS FROM MOMORDICA-CHARANTIA [J].
GUEVARA, AP ;
LIMSYLIANCO, CY ;
DAYRIT, FM ;
FINCH, P .
PHYTOCHEMISTRY, 1989, 28 (06) :1721-1724
[8]
Momordica charantia constituents and antidiabetic screening of the isolated major compounds [J].
Harinantenaina, Liva ;
Tanaka, Michi ;
Takaoka, Shigeru ;
Oda, Munehiro ;
Mogami, Orie ;
Uchida, Masayuki ;
Asakawa, Yoshinori .
CHEMICAL & PHARMACEUTICAL BULLETIN, 2006, 54 (07) :1017-1021
[9]
Cucurbitane-type triterpenoids from the fruit of Momordica charantia [J].
Kimura, Y ;
Akihisa, T ;
Yuasa, N ;
Ukiya, M ;
Suzuki, T ;
Toriyama, M ;
Motohashi, S ;
Tokuda, H .
JOURNAL OF NATURAL PRODUCTS, 2005, 68 (05) :807-809
[10]
Kuo Yao-Haur, 2001, Chinese Pharmaceutical Journal (Taipei), V53, P257