Together until separin do us part

被引：19

作者：

Amon, A ^{[1
]}

机构：

[1] MIT, Ctr Canc Res, Howard Hughes Med Inst, Cambridge, MA 02139 USA

来源：

NATURE CELL BIOLOGY | 2001年 / 3卷 / 01期

关键词：

D O I：

10.1038/35050642

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Loss of sister-chromatid cohesion triggers chromosome segregation. Several recent reports show that the protease Esp1 cleaves the cohesin subunit Scc1/Mcd1 to induce sister-chromatid segregation in yeast and vertebrates. This finding indicates that cohesin cleavage may control sister-chromatid separation in all eukaryotes.

引用

页码：E12 / E14

页数：3

共 19 条

[1] Disjunction of homologous chromosomes in meiosis I depends on proteolytic cleavage of the meiotic cohesin Rec8 by separin [J].

Buonomo, SBC ;

Clyne, RK ;

Fuchs, J ;

Loidl, J ;

Uhlmann, F ;

Nasmyth, K .

CELL, 2000, 103 (03) :387-398

[2] Characterization of the components of the putative mammalian sister chromatid cohesion complex [J].

Darwiche, N ;

Freeman, LA ;

Strunnikov, A .

GENE, 1999, 233 (1-2) :39-47

[3] MEI-S332, A DROSOPHILA PROTEIN REQUIRED FOR SISTER-CHROMATID COHESION, CAN LOCALIZE TO MEIOTIC CENTROMERE REGIONS [J].

KERREBROCK, AW ;

MOORE, DP ;

WU, JS ;

ORRWEAVER, TL .

CELL, 1995, 83 (02) :247-256

[4] Sister chromatid cohesion: the beginning of a long and beautiful relationship [J].

Koshland, DE ;

Guacci, V .

CURRENT OPINION IN CELL BIOLOGY, 2000, 12 (03) :297-301

[5] Identification of Xenopus SMC protein complexes required for sister chromatid cohesion [J].

Losada, A ;

Hirano, M ;

Hirano, T .

GENES & DEVELOPMENT, 1998, 12 (13) :1986-1997

[6] Identification and characterization of SA/Scc3p subunits in the Xenopus and human cohesin complexes [J].

Losada, A ;

Yokochi, T ;

Kobayashi, R ;

Hirano, T .

JOURNAL OF CELL BIOLOGY, 2000, 150 (03) :405-416

[7]

MIYAZAKI WY, 1994, ANNU REV GENET, V28, P167, DOI 10.1146/annurev.ge.28.120194.001123

[8] Splitting the chromosome: Cutting the ties that bind sister chromatids [J].

Nasmyth, K ;

Peters, LM ;

Uhlmann, F .

SCIENCE, 2000, 288 (5470) :1379-1384

[9] The APC is dispensable for first meiotic anaphase in Xenopus oocytes [J].

Peter, M ;

Castro, A ;

Lorca, T ;

Le Peuch, C ;

Magnaghi-Jaulin, L ;

Dorée, M ;

Labbé, JC .

NATURE CELL BIOLOGY, 2001, 3 (01) :83-87

[10] SCF and APC: the Yin and Yang of cell cycle regulated proteolysis [J].

Peters, JM .

CURRENT OPINION IN CELL BIOLOGY, 1998, 10 (06) :759-768

← 1 2 →