Necrotizing enterocolitis and apnoeas-bradycardias of the preterm newborn

被引:2
作者
Blond, MH [1 ]
Chavet, MS
Lecuyer, AI
Ajam, E
Henrot, A
Gold, F
Laugier, J
Saliba, E
Letenneur, L
机构
[1] CHU Tours, Serv Med Neonatale, Ctr Pediat Gatien de Clocheville, F-37044 Tours 1, France
[2] CHU Tours, Unite Informat Med & Econ Sante, Hop Bretonneau, F-37044 Tours 1, France
[3] CHU Tours, Ctr Pediat Gatien de Clocheville, Unite Pediat Soins Intensifs, F-37044 Tours 1, France
[4] Univ Victor Segalen, INSERM U330, F-33076 Bordeaux, France
来源
ARCHIVES DE PEDIATRIE | 2003年 / 10卷 / 02期
关键词
enterocolitis necrotizing; risk factors; infant; newborn;
D O I
10.1016/S0929-693X(03)00305-1
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Population and methods - All cases of confirmed NEC matched to controls for identical gestational age and period of hospitalization; apnoeas-bradycardias prospectively counted. Results - Forty-five cases were compared to 89 controls. The isolated risk factors were: an intra-uterine growth retardation (OR = 3,65, 95% confidence interval {CI} 95%: 1,54-8,63); a birth weight < 1000 g (OR = 8,16, CI 95%: 1,17-56,62), compared to a weight greater than or equal to 1500 g; a triple antibiotherapy (OR = 6,15, CI 95%: 1,16-32,45); an umbilical venous catheterization (OR = 2,64, CI 95%: 1,09-6,44); a number of simple apnoeas-bradycardias greater than or equal to 3rd tercile (n = 27) (OR = 4,54, CI 95%: 1,29-15,93), or severe (stimulated or with hypoxia) apnoeas-bradycardias 3rd tercile (n = 8) (OR = 6,15, CI 95%: 1,59-23,75); an haemoglobin level lower than the 1(st) tercile (95 g/L) (OR = 5,90, CI 95%: 1,20-20,13); and milk thickening by Gumilk((R)) (OR = 2,78, CI 95%: 1,11-6,90). Conclusion - In the present practices, anoxo-ischemic factors during the first week of life do not represent an important risk of NEC; a great vigilance must be exercised for indications of the triple antibiotherapy and the treatment of apnoeas-bradycardias. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
引用
收藏
页码:102 / 109
页数:8
相关论文
共 31 条
[31]  
WILSON R, 1983, PEDIATRICS, V71, P19