Molecular characterization of the glycoprotein genes of H5N1 influenza A viruses isolated in Israel and the Gaza Strip during 2006 outbreaks

被引：9

作者：

Perk, Shimon

Banet-Noach, Caroline

Golender, Natalia

Simanov, Lubov

Rozenblut, Ezra

Nagar, Sagit

Pokamunski, Shimon

Pirak, Michael

Tendler, Yevgenii

Garcia, Maricarmen

Panshin, Alexander

机构：

[1] Kimron Vet Inst, Div Avian & Aquat Dis, IL-50250 Biet Dagan, Israel

[2] Poultry Vet Serv, Bet Dagan, Israel

[3] Rambam Med Ctr, Haifa, Israel

[4] Univ Georgia, Coll Vet Med, Poultry Diagnost & Res Ctr, Athens, GA USA

来源：

VIRUS GENES | 2007年 / 35卷 / 03期

关键词：

H5N1 avian influenza virus; hemagglutinin; neuraminidase; phylogenetic analysis; AVIAN INFLUENZA; HEMAGGLUTININ CLEAVAGE; RECEPTOR SPECIFICITY; NEURAMINIDASE; PATHOGENICITY; VIRULENCE; SEQUENCE; BINDING; ACID; OSELTAMIVIR;

D O I：

10.1007/s11262-007-0120-1

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Highly pathogenic H5N1 avian influenza A viruses (AIV) have caused outbreaks among domestic poultry and wild aquatic birds in many Asian, European, and African countries since 1997. In March 2006 an avian H5N1 influenza A virus was isolated from poultry in Israel. In the present study we molecularly characterized the hemagglutinin (HA) and neuraminidase (NA) genes of eleven H5N1 viruses isolated from domestic poultry in Israel and Gaza in March-April 2006. Phylogenetic analysis of the HA and NA genes showed that the Israeli and Gazian viruses were closely related to viruses isolated in Egypt in 2006.

引用

收藏

页码：497 / 502

页数：6

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