Variation is the spice of life

被引：569

作者：

Kruglyak, L

Nickerson, DA

机构：

[1] Fred Hutchinson Canc Res Ctr, Genet Program, Div Human Biol, Seattle, WA 98104 USA

[2] Univ Washington, Dept Mol Biotechnol, Seattle, WA USA

来源：

NATURE GENETICS | 2001年 / 27卷 / 03期

关键词：

D O I：

10.1038/85776

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Assembling a comprehensive catalog of common human sequence polymorphisms is a key goal of the Human Genome Project. The International SNP Map Working Group has compiled a map of 1.4 million single-nucleotide polymorphisms. What fraction of all human sequence variation is captured in this collection, and what further advances are needed before the map becomes a useful tool for genetic studies?.

引用

页码：234 / 236

页数：3

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